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Acknowledgements The authors would like to acknowledge the use of artificial intelligence tools, such as ChatGPT, for assisting in literature search

In theory, targeting two different metabolic pathways could provide a synergistic effect

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NICE guidance emphasises the importance of shared decision-making in diabetes management, and your treatment regimen should be sustainable for your individual circumstances

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If you pay for the program upfront and your insurance subsequently denies the medication, Calibrate's refund policies are highly restrictive, making it an extremely high-risk option for uninsured patients