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In intraepithelial lymphocytes (IELs) and invariant natural killer T (iNKT) cells, GLP-1 medicines also induce cyclic adenosine monophosphate (cAMP) and cAMP-responsive elementbinding protein (CREB), indicating engagement of the cAMP/protein kinase A signaling pathway

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A GLP-1R agonist increases PCSK1 expression and markers of cell fate in a subcluster of cells