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This expedited review reflects the FDA's recognition of the significant unmet medical need in obesity treatment and the potential for orforglipron to expand access to GLP-1 therapy

Castle WB, Ross JB, Davidson CS, Burchenal JH, Fox HJ, Ham TH

Therefore, epigenetic biomarkers such as DNA methylation signatures and miRNA/lncRNA profiles are considered promising tools in the diagnosis of hypertension and the development of targeted therapies (Lee et al

Gastrointestinal histology

Aging is a progressive, multisystem degenerative process that begins in early adulthood and persists throughout the lifespan, ultimately contributing to a spectrum of functional disorders such as sarcopenia, osteoporosis, cardiovascular disease, neurodegeneration, and skin aging [11,12,13,14,15]