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Dibenzocyclooctadiene lignans, gomisins J and N inhibit the Wnt/-catenin signaling pathway in HCT116 cells

P., Sessa, L., Concilio, S

Areas of Ongoing Scientific Interest The following areas are receiving increasing attention in peptide research involving these compounds: Mitochondrial biogenesis and cellular energy pathways Modulation of inflammatory cytokines in epithelial tissues Wound healing and scar tissue formation Fibroblast and keratinocyte activation Copper-mediated gene regulation (via GHK-Cu) These research directions are largely being pursued in academic or pharmaceutical settings using controlled, licensed environments for laboratory-only compounds

Compared to all the metal nanoparticles tested, AuNPs have shown to possess higher cytotoxicity with IC 50 value of 37.2249.94 g/ml compared to Ag/Au bimetallic nanoparticles

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