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doi: 10.1021/acs.jmedchem.5b00726 96 DeaconCFKnudsenLBMadsenKWibergFCJacobsenOHolstJJ

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Starting at a low dose, such as 0.25 mg, allows your digestive system to gradually adapt to the medications effects

1, the post-infarction state is marked by a dysbiotic shift characterized by the depletion of beneficial SCFAs and the accumulation of pro-inflammatory mediators like TMAO and LPS, thereby exacerbating gut inflammation and potentially accelerating the pathological progression of cardiac injury 20,21