UNEX13-1E-1608) and Junta de Extremadura-FEDER (IB16006)
PHGPx protects liposomes and biomembranes from peroxidative degradation and exhibits GPx activity on phosphatidylcholine hydroperoxides
It has since been studied extensively as a model copper-carrier peptide, and is investigated for its role in skin and extracellular-matrix research, including work on collagen-related gene expression and fibroblast behaviour in cultured models
With clinically shown Lustriva proven for hair growth by increasing hair thickness
Townsend L, Dowds J, OBrien K, Sheill G, Dyer AH, OKelly B, et al
The acetyl moiety prevents the thiol group from oxidizing before absorption, shields the molecule from -GT-mediated hydrolysis in the intestinal lumen, and increases lipophilicity facilitating passive diffusion across intestinal epithelium and cell membranes