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Additionally, SIRT3 deacetylates ceramide synthases, promoting ceramide accumulation and inhibiting complex III activity 184
Maintaining a steady-state redox balance within the open metabolic system is vital, as it generates a basal redox tone at a particular setpoint
Endocr Rev (1994) 15(5):55573.10.1210/er.15.5.555 275 JenkinsPJBesserM
In the presence of peroxyl radicals, CoQ10 (ubiquinone) state becomes less reactive than the CoQ10 (ubiquinol) form
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