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Trimethylamine-N-oxide promotes vascular calcification through activation of NLRP3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3) inflammasome and NF-B (nuclear factor B) signals

It is a critical regulator of antioxidant activity, detoxification, and immune function

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Any legitimate investigation of these compounds should occur within properly authorized preclinical or clinical research under appropriate oversight, and readers should consult qualified professionals and applicable regulations before making any decisions.

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Frank now manages his AFib with medication, regular exercise and checkups