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However, clinical trial evidence shows Ozempic has superior efficacy in A1C and weight reduction compared to Trulicity over 40 weeks

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Overall, 72.5% of participants experienced at least one disruption in their GLP-1 treatment and 11.1% had multiple disruptions, Medeiros reported at ENDO 2025

Poor sleep can also slow metabolic rate, increasing the likelihood of weight gain, creating a vicious cycle

One of those methylation genes is the MTHFR gene