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Garduo-Garcia J de J, Alvirde-Garcia U, Lpez-Carrasco G, Padilla Mendoza ME, Mehta R, Arellano-Campos O, et al

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As a proof of concept, we chose to include the potent PPAR agonist WY14643 58,59,60,61 during stage 6 of the differentiation program given our observations of a relative lack of PPAR target gene expression throughout the SC- cell maturation trajectory despite a maintenance of PPAR motif activity (Figs

These results suggest that polymorphisms at positions -44 and -407 may affect gene transcription, possibly associated with reduced GLUT2 gene expression in patients with T2DM