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Studies suggest that the two peptides may also work together to reduce oxidative stress

10.3389/FENDO.2023.1261860 13 BuczyskaA.SidorkiewiczI.KociuszkoM.AdamskaA.SiewkoK.DzicioJ.et al (2023a)

While it may resemble melasma or dark spots, it is actually a type of acquired dermal pigmentation, not a true dark spot

First, peptidase enzymes present in solution (even trace amounts from manufacturing or reconstitution) become more active and cleave peptide bonds

10.1016/j.sxmr.2021.10.001 73 KilasoniyaA.GaraevaL.ShtamT.SpitsynaA.PutevichE.Moreno-ChambaB.et al (2023)

The most common issues reported by patients across both formats include mild to moderate nausea, changes in bowel habits, and a reduced desire to eat