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Abbreviations T2D: Type 2 diabetes SA: Sleep apnea GLP-1RAs: Glucagon-like peptide-1 receptor agonists LDSC: Linkage disequilibrium score regression MR: Mendelian Randomization IVW: Inverse-variance weighted GWAS: Genome-wide association study eQTL: Expression quantitative trait loci SNP: Single nucleotide polymorphism HbA1c: Glycated hemoglobin A1c OSA: Obstructive sleep apnea CSA: Central sleep apnea AHI: Apneahypopnea index NAFLD: Non-alcoholic fatty liver disease RCT: Randomized controlled trials IV: Instrumental variables References Galicia-Garcia U, Benito-Vicente A, Jebari S, Larrea-Sebal A, Siddiqi H, Uribe KB, et al

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Toxicity is usually due to exceeding the recommended daily dosage, often occurring due to accidental combination use of multiple products containing acetaminophen or through changes in dosage amounts by manufacturers

El uso durante embarazo y lactancia se desaconseja por insuficiente evidencia especfica de seguridad en dosis suplementarias concentradas, a pesar de que la L-Carnitina es un compuesto endgeno y est presente naturalmente en la leche materna en concentraciones variables