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Pregnant or breastfeeding women Individuals with a history of medullary thyroid carcinoma (MTC) Patients with multiple endocrine neoplasia type 2 (MEN2) Children and adolescents Those with significant GI motility disorders (unless cleared by a physician) Possible Side Effects of Cagrilintide Cagrilintide is generally well tolerated, but may cause: Nausea (dose-related) Decreased appetite Mild headache or fatigue GI side effects often resolve with slow dose titration

J Appl Physiol

Specialized stable versions designed for oral use offer better survival through the gastrointestinal tract

Zemba Cilic et al., 2021)

Here, using a several times higher cuprizone diet, followed by concomitant additional intragastrical administrations of huge cuprizone quantity, we clearly exaggerate and speed up the damaging process