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Any references to overlapping pathway activity are included solely for scientific context and do not imply that the blend is intended to heal, regenerate, or treat any condition

doi: 10.3389/fbioe.2025.1706245 Received 16 September 2025 Accepted 02 October 2025 Published 13 October 2025 Volume 13 - 2025 Edited by Luyun Cai, Bohai University, China Reviewed by Zhongxiang Li, Jinan University, China Zhanghui Chen, Central Peoples Hospital of Zhanjiang, China Updates Copyright 2025 Rana, Saifullah, Saeid, Kamal, Gao and Gao

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These findings are documented but derive predominantly from animal studies and should be interpreted accordingly

Both patients with T2DM (24 studies) and those without T2DM were included

If levels are too low, metabolic health issues are more likely to pop up, whereas higher levels are linked to improved glucose control, reduced appetite, and enhanced fat metabolism