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Chemical modifications, such as amino acid mutations, addition of fatty acid chains, or design of synthetic analogs, can enhance their resistance to enzymatic degradation and significantly improve metabolic stability and half-life (Yu et al., 2018

Weight fluctuations, sun exposure, and lifestyle factors can accelerate this decline

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Societal standards only exacerbate it, causing loose skin to feel like a defect, even when it signifies wonderful advancement

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