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doi: 10.1016/J.METABOL.2020.154304 35 NatalicchioALabarbutaRTortosaFBiondiGMarranoNPeschecheraAet al

Although the purpose of the study was not to conduct quantitative analyses, questionnaire data showed a trend towards reduction in PHQ-9, GAD-7 and EDE-Q scores (Table 1), which were clinically significant given that change scores of 5, 4 and 0.57 are considered the minimal clinically important differences in PHQ-9, GAD-7 and total EDE-Q scores respectively [38,39,40]

This is an increasingly popular tactic in internet communities, although clinical impact at smaller doses can differ

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You pull the vial out for your weekly dose, get distracted by a phone call, and suddenly two hours have passed