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Typical side effects include nausea, headache, facial flushing, and localized hyperpigmentation, generally mild to moderate and self-limiting
While acute administration in humans may potentially enhance performance [25], the majority of studies suggest no benefit [23, 2630]
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Interestingly, surface-targeted LaccID gave much cleaner localization to the cell surface than surface-targeted APEX2 or HRP, which exhibited substantial pools of trapped intracellular protein (Fig
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