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R., Gray, A
Global protein abundance profiling by mass spectrometry Sample preparation (A) Flash frozen liver sections (~25 mg) from WT or Gclc / mice (3 biological replicates each per TMT sample) were thawed on ice and resuspended in DPBS, supplemented with protease (cOmplete, EDTA-free protease inhibitor cocktail, Roche, #11873580001) and phosphatase (PhosSTOP, Roche, #4906845001) inhibitor tablets
miR-1246, released via exosomes from CRC cells, can reprogram tumor-associated macrophages (TAMs) toward a pro-tumor phenotype by altering their metabolic state, thereby supporting CRC growth and immune evasion [115]
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