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Heterogeneity was 25.77% with no evidence of publication bias on visible inspection of the funnel plot (Supplemental Fig

Studies indicate that probiotics can increase the abundance of beneficial bacteria, inhibit the growth of pathogens, and promote the production of SCFAsthereby enhancing immune function ( In a Chd8 deficient mouse model, excessive epithelial proliferation and microvillus abnormalities were linked to BBB dysfunction and microglial activation

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Vannuccini and Petraglia, 2019

The 2023 NEEL gel IRB study reported collagen-density change at 3 months