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Consuming 10 grams of pure inulin or oligofructose in a single meal or 20 grams through the day FIBRULINE chicory root fibre, inulin and FIBRULOSE chicory root fibre, oligofructose provides a substantial part of the daily recommended total fibre intake and is both effective and well-tolerated for adults

And I think that would have been fascinating

In the SURMOUNT-1 trial, side effects included: Nausea (31.0%) Diarrhoea (23.0%) Constipation (17.0%) Vomiting (12.0%) Despite higher weight loss than semaglutide in some studies, tolerability varies by individual

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This is upstream of histamine release, meaning it prevents the problem rather than managing its consequences

Over time, thats where prevention gets missed and prevention can lead to long-term savings