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Results Construct design for selecting high-GSH cells As cellular GSH is known to feedback inhibit expression from the GSH1 promoter ( pGSH1 ) [30], we designed a feedback loop for enrichment of high-GSH producing cells within clonal yeast cultures (Fig

Sodium and calcium are relatively low

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While higher doses (particularly 54 mg) showed some increase in gastrointestinal-related events, these remained mild to moderate in severity and did not result in treatment discontinuation