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However, those already on blood pressure medications should be monitored closely, as GLP-1-induced blood pressure reductions could necessitate antihypertensive dose adjustments to prevent hypotension or orthostatic symptoms

Blood Cells Mol Dis

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By contrast, no significant changes in 4HNE levels were observed across groups, indicating selective modulation of oxidative stress markers [2]

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Comparative Studies with IGF-1 A significant body of research has focused on comparing IGF-DES with native IGF-1 to understand the role of IGFBPs in modulating growth factor activity