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[DOI] [PubMed] [Google Scholar] 115.Devadas S, Hinshaw JA, Zaritskaya L, Williams MS

But timing mistakes reduce effective dose by 3040%, turning a precision NNMT inhibitor into a variable-outcome experiment

It may also potentiate the tumoricidal effect of methotrexate (MTX) since polyglutamation of MTX impairs its efflux from tumor cells and reduces its accumulation in the gut (31)

Note that this study used the parent compound epithalamin rather than the synthetic tetrapeptide Epithalon