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At higher total doses like 8mg or 12mg, split dosing is more likely to maintain adequate peak concentrations for glucagon activation because each individual injection is still a substantial amount

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In a phase 2b randomized clinical trial, bofanglutide demonstrated a strong efficacy in reducing blood sugar in people with type 2 diabetes

Native oxyntomodulin has significant glucoregulatory effects independent of weight loss in obese humans with and without type 2 diabetes

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