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Figure 1 4 Evidence framework and phenotypic heterogeneity of GLP-1RA-associated taste-related changes In real-world obesity treatment, some patients receiving GLP-1RAs report changes in eating experience, such as food tastes different, food is no longer appealing, or the emergence of unpleasant taste sensations (66) to broader concepts such as food taste change or patient-reported alterations in flavour evaluation (67)