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The enigmatic persistence of anorexia nervosa

The therapeutic effect is achieved by reducing FA and cholesterol synthesis through the inhibition of ACLY (143)

Acetyl-CoA is also an allosteric activator of pyruvate carboxylase that catalyzes the gluconeogenesis pathway which is active during catabolic states such as fasting.[6][15][16] In carnitine deficient states, LCFAs cannot be effectively transported to the mitochondria matrix for oxidation and subsequent utilization in Krebs cycle and ketone body production

1-12, Mansour, Meghan R., et al

Si baja la ingesta de protenas, la musculatura puede verse afectada