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And thats a good sort of parameter and a surrogate to measure whether theyre doing that or not

Neuropsychopharmacology, 45, 1656-1663

Oral anti-diabetic drugs and fracture risk, cut to the bone: safe or dangerous

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if oral colon targeting is pursued, gastric protection (e.g., Eudragit S or enzymatically degradable polysaccharides), steric stabilization (cholesterol/PEG-lipids), and mucus-penetration strategies will be required

Research references The published record