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While they work well for some users, they may increase appetite more than desired

Kopp K, Glotfelty E, Li Y, et al (2023) Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment

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Therefore, women of childbearing age should be advised that significant weight loss may increase fertility, requiring effective contraception