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3-month-old female mice (WT or GCLC-KO) were fed with PLX3397 formulated-chow or control chow for 2 months, and brain samples were collected immediately after the end of the feeding period

360 Since transcriptional induction of 2-integrin gene expression plays a vital role in macrophage function, work was undertaken to identify the causative molecular mechanisms

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Besides the interleukin family, other genes related to the skin inflammatory mechanism were also upregulated

Alfthan G, Aro A, Arvilommi H, Huttunen JK