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In fact, polylysine at alkaline pH and polyglutamic acid at acid pH form -helical conformations, since under these conditions they have neutral side chains, whereas at high pH and high temperature, polylysine adopts an extended, flat, multistranded -sheet conformation, and polyglutamic acid forms -sheet structure at low pH
Peer review Peer review information Nature Reviews Endocrinology thanks Thomas Lutz and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
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Studies and clinical experience show that lipotropic injections work best when coupled with a calorie-restricted diet, regular resistance or aerobic exercise, and behavior-change coaching rather than as stand-alone therapy
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