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Rac1 also activates the Wave Regulatory Complex (WRC, composed by five proteins: CYFIP1, NCKAP1, Abi2, HSPC300, and WAVE1) by directly binding CYFIP1 and leading to Arp2/3 complex-mediated actin polymerization (139141)

doi: 10.1111/j.1365-2265.1995.tb02929.x 103 RaunKHansenBSJohansenNLThogersenHMadsenKAnkersenMet al

These findings offer valuable insights into the metabolic underpinnings of epilepsy, laying the groundwork for targeted therapies