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Impurities in either vial will ruin a comparative study

Some biomarkers (oxidative stress, antioxidant capacity) may shift within 24 weeks, while functional improvements may take 812 weeks or longer depending on dose, route, and baseline status

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Additionally, DSIP contains a glutamic acid residue at the C-terminus and aspartic acid in the chain, both of which are susceptible to deamidation and cyclization side reactions under non-neutral pH conditions, particularly at elevated temperatures

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