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Moreover, it has been shown that hyperuricemia (also observed in our study) can cause significant changes in systemic and renal hemodynamics, which may result in the loss of autoregulatory kidneys function 54

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The dose was subsequently increased to 5 mg without recurrence

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For early stratification, future studies should test panels that combine conventional severity assessment with circulating indicators of mitochondrial injury and organelle-network stress, particularly mitochondrial DNA release and related inflammatory readouts detectable in patients (99)

[17] Any additional hormonal or pituitary-modulating agents should only be used with HCG under medical supervision due to the potential for complex endocrine interactions