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EncarnaoJCPiresASAmaralRAGonalvesTJLaranjoMCasalta-LopesJEet al

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The inflammatory environment in AD triggers the release of cytokines such as interleukin-1 (IL-1) and tumor necrosis factor- (TNF-), which can reduce GLUT expression in brain cells

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Although these therapies have effectively managed symptoms and decelerated disease progression, long-term use is often associated with severe adverse effects, including increased infection risk, osteoporosis, metabolic disorders, and the likelihood of malignant tumors (6, 7)