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LPS exposure triggers NF-B activation, which begins with the phosphorylation of IB, an NF-B inhibitor, by specific kinases
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Electroencephalograms (EEGs) in patients with MELAS typically show diffuse background slowing, often accompanied by slow waves mixed with sharp waves, especially in the bilateral anterior regions (28)
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16 Currently, steroidal and non-steroidal anti-inflammatory drugs (NSAIDs) are used for the treatment of OA, but these treatments fail to reverse disease progression
A third approach, which our laboratory has been pursuing exploits a step in the activation process of the HGF-Met system
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