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As anticipated, during EA treatment, the suppression of GLP-1 neurons resulted in an increase in the rats' weight gain rate, Lee's index, and 24-h food intake

Although ROS play essential roles in the maintenance of basal cellular activities such as chondrocyte proliferation and matrix remodeling in cartilage, excessive oxidative stress causes detrimental events such as cellular senescence 36,121 , dedifferentiation 122 , and apoptosis 123

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