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These studies suggest that BECN1 can promote ferroptosis by inhibiting the activity of the Xc-system

This also highlights the need for consideration of haem source in in vitro models, where free haem is typically added as the sole source in culture media: a condition which may not reflect predominant sources in the respiratory and middle ear niches

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Common side effects include nausea, stomach discomfort, and potential allergic reactions

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