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[1] This mechanism can have variable effects on IBS symptoms depending on the predominant bowel pattern

Patients should also seek medical advice if muscle symptoms are accompanied by systemic features such as fever, unexplained weight loss beyond what is expected from GLP-1 therapy, rash, joint swelling, or other concerning signs that might suggest inflammatory or autoimmune conditions

GLP-1 receptors in the brain, CGRP reduction, neuroinflammation suppression, intracranial pressure reduction, these all point in the same direction

We encourage you to reflect on your daily rhythm and how you typically react to new medications

Representative compounds include deferoxamine (DFO), deferiprone (DFP), and the novel metal-modulating molecule PBT2 (He et al., 2024

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