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A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy

A strong maintenance plan should protect muscle, support nutrition, monitor metabolic health, manage side effects, and reduce the risk of regain

Health professionals must alert their patients about the potential for drug-induced severe depression as a side effect

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[1] Dose-escalation studies, such as a 12-week trial on gradual titration, revealed that beginning at lower doses (e.g., 4 mg) and slowly increasing to therapeutic levels significantly reduced the incidence of nausea, vomiting, and diarrhoea

This dual-action approach addresses both the hormonal and behavioral components of weight management, which is why some practitioners recommend combination therapy