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3.5 Neurotrophic deficits and impaired hippocampal neurogenesis The diminishment of neurotrophic signaling, especially that related to brain-derived neurotrophic factor (BDNF), stands as a defining characteristic of depression

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Subsequently, through the action of divalent metal transporter 1 (DMT1), Fe 2+ enters from the endosomes to the labile iron pool (LIP) in the cytoplasm [71]

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