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The structural comparison indicates that the GHSR-G i complex in our structures resembles the canonical NTSR1-G i state with a similar G i interaction profile (Fig

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Stimulation of NO production via the NOS-dependent pathway nNOS and eNOS are calciumcalmodulin-dependent enzymes responsible for the conversion of L-arginine and oxygen to L-citrulline and NO (Ignarro, 1990

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