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While activated CD4 + helper T cell 1 (Th1) cells fight cancer by secreting interferon- (IFN-) to activate macrophages and natural killer (NK) T cells, activated CD8 + T cells have direct cytotoxic effects against tumors [57] (Fig

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Peripheral blood dendritic cells and GM-CSF as an adjuvant for hepatitis B vaccination in hemodialysis patients

Notably, treatment with GABA and specific interventions using DSIP-CBBBP and DSIP markedly decreased immobility times compared to the model group, suggesting their effectiveness in mitigating depressive-like behaviors