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Safety and efficacy for human use have not been established through adequate and well-controlled studies

In 2005, more than 15 years later, the first GLP-1 drug for diabetes was approved

It compared nearly 216,000 people who were prescribed GLP-1 medications to people prescribed three other kinds of medications to lower their blood sugar, as well as those who enrolled in the system with diabetes who continued to take the medications they had already been prescribed without any changes to their therapy, meaning they didnt start a new drug during this time

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Future studies should aim to replicate the findings, ideally with a larger sample size to increase statistical power

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