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Ischemic Injuries Ischemic-reperfusion (I/R) injuries such as myocardial infarction and stroke are primarily associated with systemic inflammation, a burst of circulating ROS, and organ damage from cell death

Conen D, Glynn RJ, Buring JE, Ridker PM, Zee RY

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Journal of Substance Abuse Treatment, 31 , 59-65

It adds that tirzepatide carries established safety monitoring for nausea, gastrointestinal side effects and rarer risks such as pancreatitis or thyroid concerns, so provider oversight applies whether or not lipotropics are added to the regimen