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4 , 5 This uncertainty in DDI potential is particularly problematic when initiating GLP1RA therapy in patients taking narrow therapeutic index medications, such as oral anticoagulants, anticonvulsants, and hormonal contraceptives

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Therefore, both KD and ketogenic supplementation of regular diet seem to have neuroprotective effects mediated by A 1 R and possibly also A 2 R receptors (Figure 2)