Factors accelerating tolerance include consistent calorie restriction without adequate protein, insufficient water intake, sedentary behavior, and rapid dose escalation followed by long plateaus at a single dose
Copper can oxidize vitamin C, reducing its effectiveness
While previous research has shown that stopping GLP-1s can lead to weight gain, this latest study suggests that greater weight loss tends to result in faster weight regain, especially when these blockbuster drugs are involved
This is primarily due to a lack of clinical researchbreastfeeding women are routinely excluded from medication trials, which means we dont have robust data on how these drugs might affect a breastfeeding parent or their baby
Di Martino et al
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