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In cell studies, the complex stimulates fibroblasts to produce types I, III and IV collagen, elastin and glycosaminoglycans, while down-regulating matrix metalloproteinases that break down the skins scaffold.(pubmed.ncbi.nlm.nih.gov) These actions form the biochemical basis for its cosmetic before and after effects

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10.3748/wjg.v28.i25.2843 2 AlberghinaM.LupoG.La SpinaG.MangiameliA.GulisanoM.SciottoD.et al (1992)