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Alternatively, altered genetic regulation of Gpx4 expression caused by overexpression of mutated APP and PS1 in transgenic animals, may have disturbed the normal gene expression pattern, as it has been recently demonstrated to occur in the frontal cortex and hippocampus of transgenic mice carrying the E9 mutant hPS1 gene (Unger et al., 2005)
The research says that the potent antioxidant action of ascorbic acid might be responsible for the observed reduction of the erythema of rosacea, in which free-radical production plays a role in the inflammatory response to triggers
Nutrients 2021;13:2830
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