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Lefvre et al., 2010), senescent cells have also been shown to change their phenotype, secreting proinflammatory cytokines and contributing to systemic low-grade inflammation ( Hematopoietic progenitor and lymphoblastoid cell toxicity of NRTIs may explain immune cell depletion independent of inflammation (Sundseth et al., 1996

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The improved potency comes with a side effect profile that remains significantly more problematic than ipamorelin