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Glutathione has one of the most extensive published research bases in cellular biochemistry, with thousands of peer-reviewed studies spanning its antioxidant function, enzyme cofactor roles, redox signalling activity, and disease relevance across cancer, neurodegeneration, metabolic disease, and immunology

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20shows complete protection of spiral ganglion neurons (SGNs) from cisplatin-induced degeneration in a cochlear explant model with 1.5 hour pretreatment followed by co-treatment with the otoprotectant 6-thioguanine with 10 M cisplatin